GMAT Practice Question Set #12 (Question 34-36)

Critical Reasoning Question #34: Cause of Osteosarcoma  
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The primary cause for osteosarcoma, the most common form of primary bone cancer, is not known. Researchers believe that infection by the SV40 virus is a possible contributing cause, since recent investigations have identified SV40 DNA sequences in tissue samples from osteosarcomas, but no SV40 DNA sequences were found in healthy tissue. SV40 is a monkey virus; however, in 1960 some polio vaccine was contaminated with the virus. Researchers hypothesize that this vaccine was the source of the virus found in osteosarcomas decades later.

Which of the following, if true, most strongly supports the researchers' hypothesis?


SV40 is widely used as a research tool in cancer laboratories.


Changes in the technique of manufacturing the vaccine now prevent contamination with SV40.


Recently discovered samples of the vaccine dating from 1960 still show traces of the virus.


In Finland, where the polio vaccine was never contaminated, samples from osteosarcomas do not contain SV40.


In a small percentage of cases of osteosarcoma, there is no history of exposure to the SV40 monkey virus.

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